POSITIONS AVAILABLE!

Help us understand the role of non-coding RNAs in stress and aging

Send your CV and a description of your interest in joining our team to apasquinelli@ucsd.edu

UC San Diego School of Biological Sciences
Department of Molecular Biology

Role of the miRNA Pathway in Aging

Reviews

Elder CR, Pasquinelli AE. New roles for microRNAs in old worms. Front Aging. 2022 Apr 12;3:871226. doi: 10.3389/fragi.2022.871226. eCollection 2022.PMID: 35821862. PMCID: PMC9261348

Primary Research
Chipman LB, Luc S, Nicastro IA, Hulahan JJ, Dann DC, Bodas DM, Pasquinelli AE. Expression, not sequence, distinguishes miR-238 from its miR-239ab sister miRNAs in promoting longevity in Caenorhabditis elegans. PLoS Genet. 2023 Nov 27;19(11):e1011055. doi: 10.1371/journal.pgen.1011055. eCollection 2023 Nov. PMCID:PMC10703411
 

Aalto AP, Nicastro IA, Broughton JP, Chipman LB, Schreiner WP, Chen JS, Pasquinelli AE. Opposing roles of microRNA Argonautes during Caenorhabditis elegans aging. PLoS Genet. 2018 Jun 21;14(6):e1007379. doi: 10.1371/journal.pgen.1007379. eCollection 2018 Jun. PMCID: PMC6013023

Studying the role of the miRNA pathway in aging C. elegans